Disease: Malignant Neoplasms
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNFRSF10A O00220 TNF receptor superfamily member 10a 5.1E-15 0.521 0.731
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SLC5A5 Q92911 solute carrier family 5 member 5 Transporter 2.9E-03 0.499 0.769
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
PLAUR Q03405 plasminogen activator, urokinase receptor 5.3E-03 0.536 0.731
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PDIA3 P30101 protein disulfide isomerase family A member 3 1.00 0.566 0.769
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NAT1 P18440 N-acetyltransferase 1 Enzyme 1.9E-14 0.536 0.846
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
KDM6A O15550 lysine demethylase 6A Epigenetic regulator 1.00 0.498 0.769